|
Symbol Name ID |
Foxl2
forkhead box L2 MGI:1349428 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypoplasia of the uterus |
Premature ovarian insufficiency |
Amenorrhea |
Secondary amenorrhea |
Irregular menstruation |
Female infertility |
| Disease(s) Associated with FOXL2 | ||||||
| blepharophimosis, ptosis, and epicanthus inversus syndrome | ||||||
| primary ovarian insufficiency 3 |
| Mouse Phenotypes | reproductive system phenotype |
oligozoospermia |
impaired granulosa cell differentiation |
asthenozoospermia |
immotile sperm |
decreased granulosa cell proliferation |
abnormal ovary morphology |
decreased corpora lutea number |
abnormal ovarian follicle morphology |
absent mature ovarian follicles |
absent primordial ovarian follicles |
absent secondary ovarian follicles |
increased atretic ovarian follicle number |
impaired ovarian folliculogenesis |
abnormal ovary size |
decreased ovary weight |
small ovary |
abnormal seminiferous tubule morphology |
decreased Sertoli cell number |
decreased testis weight |
small testis |
abnormal ovary physiology |
abnormal testis physiology |
arrest of male meiosis |
abnormal spermatogenesis |
arrest of spermatogenesis |
primary sex reversal |
delayed vaginal opening |
decreased ovulation rate |
prolonged estrus |
female infertility |
reduced female fertility |
decreased litter size |
reduced male fertility |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
| Foxl2tm1Gpil/Foxl2tm1Gpil | |||||||||||||||||||||||||||||||||||
| Foxl2tm1Tre/Foxl2tm1Tre | * | ||||||||||||||||||||||||||||||||||
| Foxl2tm3Tre/Foxl2tm3Tre | * | ||||||||||||||||||||||||||||||||||
| Foxl2tm4(cre)Tre/Foxl2tm4(cre)Tre | * | ||||||||||||||||||||||||||||||||||
| Foxl2tm1Tre/Foxl2+ | |||||||||||||||||||||||||||||||||||
| Foxl2tm4(cre)Tre/Foxl2+ | * | ||||||||||||||||||||||||||||||||||
| Foxl2tm2.1Tre/Foxl2tm2.1Tre Gt(ROSA)26Sortm9(cre/ESR1)Arte/? (conditional) |
|||||||||||||||||||||||||||||||||||
| Foxl2tm2.1Tre/Foxl2tm2.1Tre Tg(Cga-cre)3Sac/0 (conditional) |
|||||||||||||||||||||||||||||||||||
| Foxl2tm2.1Tre/Foxl2tm2.1Tre Tg(Gdf9-icre)5092Coo/0 (conditional) |
* | ||||||||||||||||||||||||||||||||||
| Foxl2tm2.1Tre/Foxl2tm2.1Tre Gnrhrtm1.1(cre)Uboe/Gnrhr+ (conditional) |
|||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools